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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ORC1L All Species: 20
Human Site: S383 Identified Species: 36.67
UniProt: Q13415 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13415 NP_004144.2 861 97350 S383 P H R I R R K S S V L T M N R
Chimpanzee Pan troglodytes XP_513408 861 97367 S383 P H R I R R K S S V L T M N R
Rhesus Macaque Macaca mulatta XP_001111614 860 97440 S382 P R H I R R K S S V L S M N R
Dog Lupus familis XP_532575 858 97161 S381 S H R I R R K S S F L T L N R
Cat Felis silvestris
Mouse Mus musculus Q9Z1N2 840 95057 T362 R K A K E Q E T H K E P I R T
Rat Rattus norvegicus Q80Z32 848 95741 S370 S L R A R R R S S L L T L K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026457 858 96850 S381 R T C T Q E T S T R I A E Q I
Frog Xenopus laevis NP_001081806 886 99953 A409 P R S R R T S A R K T A N K V
Zebra Danio Brachydanio rerio NP_956227 910 101179 I432 I R K Q L N L I A N K F D L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O16810 924 103263 S447 P R R S I H L S N I V E Q R V
Honey Bee Apis mellifera XP_392056 490 55682 E29 K Q K R M I C E T P K K I Q C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798977 905 100707 D420 V L H W L K Q D A E S K D I P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567440 809 91877 L343 S F K R V A E L A D G D E D S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 94.7 81.5 N.A. 66 69.8 N.A. N.A. 50.5 52.4 48.6 N.A. 33.4 31.8 N.A. 29.7
Protein Similarity: 100 98.9 97.3 88.8 N.A. 77.9 79.9 N.A. N.A. 66.3 67 63.1 N.A. 52.7 43.5 N.A. 47.1
P-Site Identity: 100 100 80 80 N.A. 0 53.3 N.A. N.A. 6.6 13.3 0 N.A. 20 0 N.A. 0
P-Site Similarity: 100 100 86.6 86.6 N.A. 26.6 73.3 N.A. N.A. 26.6 20 20 N.A. 40 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 27.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 8 0 8 24 0 0 16 0 0 0 % A
% Cys: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 8 0 8 0 8 16 8 0 % D
% Glu: 0 0 0 0 8 8 16 8 0 8 8 8 16 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 8 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 24 16 0 0 8 0 0 8 0 0 0 0 0 0 % H
% Ile: 8 0 0 31 8 8 0 8 0 8 8 0 16 8 8 % I
% Lys: 8 8 24 8 0 8 31 0 0 16 16 16 0 16 0 % K
% Leu: 0 16 0 0 16 0 16 8 0 8 39 0 16 8 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 24 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 8 8 0 0 8 31 0 % N
% Pro: 39 0 0 0 0 0 0 0 0 8 0 8 0 0 8 % P
% Gln: 0 8 0 8 8 8 8 0 0 0 0 0 8 16 8 % Q
% Arg: 16 31 39 24 47 39 8 0 8 8 0 0 0 16 39 % R
% Ser: 24 0 8 8 0 0 8 54 39 0 8 8 0 0 8 % S
% Thr: 0 8 0 8 0 8 8 8 16 0 8 31 0 0 8 % T
% Val: 8 0 0 0 8 0 0 0 0 24 8 0 0 0 16 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _